Sandro Pereira • 1/27/2026

BizTalk Server and WinSCP Error: Could not load file or assembly ‘WinSCPnet, Version=1.16.0.16453, Culture=neutral, PublicKeyToken=2271ec4a3c56d0bf’ or one of its dependencies.

This article details a troubleshooting process for a specific System.IO.FileLoadException error when configuring the SFTP adapter in BizTalk Server 2020. It explains the cause—version mismatch between WinSCP and BizTalk Server Cumulative Updates—and provides a clear solution, including a compatibility matrix and steps to copy the correct WinSCP files or use an automated PowerShell script.

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#Net Framework #Biztalk Server #Winscp